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Xaira launches with $1B+ for AI drug development

In one of the biggest startups ever, Xaira Therapeutics has launched with more than $1 billion from investors. The financing, according to BioWorld records, is roughly equivalent to Roivant Sciences Inc.โ€™s $1.1 billion raise in August 2017 and Galderma Inc.โ€™s $1 billion private placement in June 2023.
Galderma Inc Roivant Sciences Inc Xaira Therapeutics Roivant Sciences Machine Learning Bioworld Science

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Outrun emerges from stealth with $10M for E3 ligase inhibitors

Newco Outrun Therapeutics Ltd. has raised $10 million in a seed round to develop small-molecule E3 ubiquitin ligase inhibitors that prevent programmed protein degradation. The lead program targeting an E3 ligase that tags a tumor suppressor protein for destruction will now advance to preclinical development.
Newco Outrun Therapeutics Ltd Newco Outrun Therapeutics Protein Degradation E3 Ligase Inhibitors Outrun Therapeutics Ltd Protein Stabilization

Cerevel undersell? Bombshell Parkinson's phase III with tavapadon

Cerevel Therapeutics Inc.โ€™s positive results from the long-shot pivotal phase III Tempo-3 trial with tavapadon โ€“ the first D1/D5 receptor partial agonist being studied as a once-daily treatment for Parkinsonโ€™s disease โ€“ added gravy to the $8.7 billion takeover by Abbvie Inc., disclosed late last year. The buyoutโ€™s centerpiece was the late-stage asset emraclidine, a positive allosteric modulator of the muscarinic M4 receptor, touted as a potential best-in-class, next-generation antipsyc...
Cerevel Therapeutics Inc Abbvie Inc Cerevel Therapeutics Cerevel Therapeutics Inc Parkinsons Disease Neurology Psychiatric

Rx, med-tech industry groups warn of impact of Gilead R&D suits

The U.S. biopharma and med-tech industries are adding their voice to that of Gilead Sciences Inc. in urging the California Supreme Court to review the Gilead Tenofovir Cases, which seek to hold the drug company liable for how and when it developed its pipeline of HIV drugs.
United States Gilead Sciences Inc California Supreme Court Gilead Sciences Gilead Tenofovir Cases Gilead Sciences Inc

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