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With programmable pixels, novel sensor improves imaging of neural activity

Neurons communicate electrically, so to understand how they produce brain functions such as memory, neuroscientists must track how their voltage changes—sometimes subtly—on the timescale of milliseconds. In a new paper in Nature Communications, MIT researchers describe a novel image sensor with the capability to substantially increase that ability.
Zeguan Wang Pedro Feliciano Ramos Jonathan Newman Matt Wilson Yong Qian Changyang Linghu

Imaging method reveals new cells and structures in human brain tissue

Using a microscopy technique known as expansion-mediated protein decrowding, researchers imaged human brain tissue in greater detail than ever before, revealing cells and structures that were not previously visible. They discovered some brain tumors called gliomas contain many more putative aggressive tumor cells than expected.
Deblina Sarkar K Lisa Yang John Doerr Edward Boyden Pablo Valdes Ed Boyden
Source: mit.edu

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