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Top-predator recovery abates geomorphic decline of a coastal ecosystem

The recovery of top predators is thought to have cascading effects on vegetated ecosystems and their geomorphology1,2, but the evidence for this remains correlational and intensely debated3,4. Here we combine observational and experimental data to reveal that recolonization of sea otters in a US estuary generates a trophic cascade that facilitates coastal wetland plant biomass and suppresses the erosion of marsh edges—a process that otherwise leads to the severe loss of habitats and ecosys...
United States Elkhorn Slough Sea Otter Enhydra Sea Otter Rr Core Team Yellowstone National Park
Source: nature.com

1-year weight change after diabetes diagnosis and long-term incidence and sustainability of remission of type 2 diabetes in real-world settings in Hong Kong: An observational cohort study

In this population based cohort study of >37,000 people in Hong Kong, Hongjiang Wu and colleagues examine 1-year weight change after diabetes diagnosis with long-term incidence and sustainability of diabetes remission.
Hong Kong University Of Hong Kong Hong Kong General Eli Lilly Merck Serono Junshi Biosciences
Source: plos.org

Tropical cyclone-specific mortality risks and the periods of concern: A multicountry time-series study

Author summary Why was this study done? Tropical cyclones (TCs), among the most destructive and costliest climate extreme events, are expected to be more intense due to climate change. Despite the widely acknowledged hazards, a consistent and quantitative assessment of the mortality risks of TC across countries is lacking. Such quantitative and comparable evidence across countries is urgently required to better understand the health effects and respond to the potentially increasing hazards. No...
United States South Korea New Zealand Puerto Rico United Kingdom Republic Of
Source: plos.org

Disproportionate declines of formerly abundant species underlie insect loss

Studies have reported widespread declines in terrestrial insect abundances in recent years1–4, but trends in other biodiversity metrics are less clear-cut5–7. Here we examined long-term trends in 923 terrestrial insect assemblages monitored in 106 studies, and found concomitant declines in abundance and species richness. For studies that were resolved to species level (551 sites in 57 studies), we observed a decline in the number of initially abundant species through time, but not in...
Minas Gerais Kurskaya Oblast Fray Jorge Iv Region Sankt Peterburg United Kingdom
Source: nature.com

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Genetic risk converges on regulatory networks mediating early type 2 diabetes

Type 2 diabetes mellitus (T2D), a major cause of worldwide morbidity and mortality, is characterized by dysfunction of insulin-producing pancreatic islet β cells1,2. T2D genome-wide association studies (GWAS) have identified hundreds of signals in non-coding and β cell regulatory genomic regions, but deciphering their biological mechanisms remains challenging3–5. Here, to identify early disease-driving events, we performed traditional and multiplexed pancreatic tissue imaging, so...
Robertc Turner Arrojoe Drigo Foundation For Statistical Computing Human Pancreas Analysis Program Islet Distribution Program International Diabetes Federation Atlas
Source: nature.com

Surgery with locking plate or hemiarthroplasty versus nonoperative treatment of 3–4-part proximal humerus fractures in older patients (NITEP): An open-label randomized trial

In a randomized controlled trial, Antti P Launonen and team compare outcomes of non-operative to operative treatment in patients aged ≥ 60 years with 3-4 part dislocated proximal humerus fractures.
Kanta Hame Region Central Finland Keski Suomi Norra Savolax Uppsala Lan Eteläuomen Läi
Source: plos.org

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