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February 1, 2024
The recovery of top predators is thought to have cascading effects on vegetated ecosystems and their geomorphology1,2, but the evidence for this remains correlational and intensely debated3,4. Here we combine observational and experimental data to reveal that recolonization of sea otters in a US estuary generates a trophic cascade that facilitates coastal wetland plant biomass and suppresses the erosion of marsh edges—a process that otherwise leads to the severe loss of habitats and ecosys...
January 23, 2024
In this population based cohort study of >37,000 people in Hong Kong, Hongjiang Wu and colleagues examine 1-year weight change after diabetes diagnosis with long-term incidence and sustainability of diabetes remission.
January 22, 2024
Author summary Why was this study done? Tropical cyclones (TCs), among the most destructive and costliest climate extreme events, are expected to be more intense due to climate change. Despite the widely acknowledged hazards, a consistent and quantitative assessment of the mortality risks of TC across countries is lacking. Such quantitative and comparable evidence across countries is urgently required to better understand the health effects and respond to the potentially increasing hazards. No...
January 19, 2024
This cohort study assesses the incidence of severe and very severe hypocalcemia in female dialysis-dependent patients aged 65 years or older receiving denosumab
December 20, 2023
Studies have reported widespread declines in terrestrial insect abundances in recent years1–4, but trends in other biodiversity metrics are less clear-cut5–7. Here we examined long-term trends in 923 terrestrial insect assemblages monitored in 106 studies, and found concomitant declines in abundance and species richness. For studies that were resolved to species level (551 sites in 57 studies), we observed a decline in the number of initially abundant species through time, but not in...
December 7, 2023
Judith Leblanc and co-workers report a cluster-randomized trial evaluating intensive screening for SARS-CoV-2 infection in emergency departments.
December 4, 2023
Type 2 diabetes mellitus (T2D), a major cause of worldwide morbidity and mortality, is characterized by dysfunction of insulin-producing pancreatic islet β cells1,2. T2D genome-wide association studies (GWAS) have identified hundreds of signals in non-coding and β cell regulatory genomic regions, but deciphering their biological mechanisms remains challenging3–5. Here, to identify early disease-driving events, we performed traditional and multiplexed pancreatic tissue imaging, so...
December 1, 2023
This randomized trial assesses whether prone vs supine positioning decreases the time to successful weaning of extracorporeal membrane oxygenation (ECMO) in pat
November 29, 2023
This clinical trial compares the efficacy of intubation withholding vs routine practice on clinical outcomes of comatose patients with acute poisoning and a Gla
November 28, 2023
In a randomized controlled trial, Antti P Launonen and team compare outcomes of non-operative to operative treatment in patients aged ≥ 60 years with 3-4 part dislocated proximal humerus fractures.