This individual participant data meta-analysis assesses treatment time from stroke symptom onset and disability level after treatment with intravenous thromboly
This study uses data from 3 prospective cohort studies conducted in the US to assess vaccine effectiveness of bivalent COVID-19 vaccines against SARS-CoV-2 infe
The recovery of top predators is thought to have cascading effects on vegetated ecosystems and their geomorphology1,2, but the evidence for this remains correlational and intensely debated3,4. Here we combine observational and experimental data to reveal that recolonization of sea otters in a US estuary generates a trophic cascade that facilitates coastal wetland plant biomass and suppresses the erosion of marsh edges—a process that otherwise leads to the severe loss of habitats and ecosystem services5,6. Monitoring of the Elkhorn Slough estuary over several decades suggested top-down control in the system, because the erosion of salt marsh edges has generally slowed with increasing sea otter abundance, despite the consistently increasing physical stress in the system (that is, nutrient loading, sea-level rise and tidal scour7–9). Predator-exclusion experiments in five marsh creeks revealed that sea otters suppress the abundance of burrowing crabs, a top-d
In this population based cohort study of >37,000 people in Hong Kong, Hongjiang Wu and colleagues examine 1-year weight change after diabetes diagnosis with long-term incidence and sustainability of diabetes remission.
Author summary Why was this study done? Tropical cyclones (TCs), among the most destructive and costliest climate extreme events, are expected to be more intense due to climate change. Despite the widely acknowledged hazards, a consistent and quantitative assessment of the mortality risks of TC across countries is lacking. Such quantitative and comparable evidence across countries is urgently required to better understand the health effects and respond to the potentially increasing hazards. No previous studies have characterized the periods of concern (POC), exposure-response (ER) relationship, and temporal trends of the TC health risks, directly relevant to more precise and effective preparedness and mitigation strategies. What did the researchers do and find? Using mortality data from 494 TC-exposed locations in 18 countries or territories, we quantified the TC-specific mortality risks and POC of the 382 TC events that affected these locations. The ER relationships and temporal