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Prone Positioning During Extracorporeal Membrane Oxygenation in Patients With Severe ARDS

This randomized trial assesses whether prone vs supine positioning decreases the time to successful weaning of extracorporeal membrane oxygenation (ECMO) in pat

France generalChristopher seymourPersonnes ouestFisher paykelR foundation for statistical computingProgramme hospitalier de recherche cliniqueService de medecine intensive reanimationInstitute of cardiometabolismGe healthcareGroup informationFresenius medical careLungpacer medical incFrench ministry of healthComite de protection des personnes ouestFrench ministryDirection de la recherche clinique

Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity

Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity
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France generalUnited statesUnited kingdomEteläuomen läiFoster citySan diegoNordrhein westfalenKatharina ibenAnna judyckaKerstin stemmerJanh britsemmerPault pflugerIngolf cascorbiMeike kaehlerJonas wagnerSonjac schriever

Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning

This clinical trial compares the efficacy of intubation withholding vs routine practice on clinical outcomes of comatose patients with acute poisoning and a Gla

France generalEteläuomen läiLe borgneYonathan freundPersonnes ouestChristopher seymourCommission nationale informatique et libertAblative solutionsAirway management of comatose poisoned emergency patientsGlasgow coma scaleNon invasive airway managementComatose poisoned emergency patientsCommission nationale informatiqueGood clinical practicePatient populationIntubation difficulty scale

Surgery with locking plate or hemiarthroplasty versus nonoperative treatment of 3–4-part proximal humerus fractures in older patients (NITEP): An open-label randomized trial

In a randomized controlled trial, Antti P Launonen and team compare outcomes of non-operative to operative treatment in patients aged ≥ 60 years with 3-4 part dislocated proximal humerus fractures.

Kanta hame regionCentral finlandKeski suomiNorra savolaxUppsala lanEteläuomen läiPeter heathSeija rautiainenR foundation for statistical computingEuroqol groupRegional ethics committee of tampere university hospitalEstonia medical centreTampere university hospitalUppsala university hospitalsTartu university hospitalKarolinska university hospital

Burden of diarrhea and antibiotic use among children in low-resource settings preventable by Shigella vaccination: A simulation study

Leveraging data from 1715 children in the MAL-ED birth cohort study, Stephanie A Brennhofer and colleagues model the expected reduction in diarrhea episodes, antibiotic use, and bystander pathogen exposure to antibiotics through the administration of Shigella vaccines.

Monte carloNepal generalUnited statesTamil naduMinas geraisSouth africaNaushero ferozeNational institute for medical researchHealth ministryChristian medical collegeFogarty international centerEmory university atlantaMelinda gates foundationThermo fisherNational ethical research committeeIndian council of medical research india