Stephan Holtkamp News Today

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental

Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms.

New research provides evidence that the migration of immune cells called dendritic cells into skin lymphatic vessels is a rhythmic process. The study showed circadian molecular clock systems in the dendritic cells and in the cells lining the lymphatic vessels are an essential and broad regulator of dendritic cell migration. This process is fundamental for the generation of adaptive immunity, the authors noted, and should prove useful to exploit in vaccination and immunotherapeutic regimens.

Swiss and German scientists show that activation of the immune system oscillates throughout the day, with a peak just before the start of the day. The