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'JAMA Neurology' publishes the results from Phase 1b/2a clinical trial of the neuroprotective drug ApTOLL for ischemic stroke

The results from APRIL study, previously presented at the International Stroke Conference 2023, indicate that ApTOLL showed good safety in 151 acute ischemic stroke patients.The article also highlights that the preliminary efficacy results show that ApTOLL significantly reduces mortality and long-term functional dis...
Israel General Lhospitalet De Llobregat Comunidad Autonoma De Cataluna Cardona Portela Macarena Hern David Segarra

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Calming overexcited neurons may protect brain after stroke - The Source - Washington University in St. Louis

By scanning the genomes of nearly 6,000 stroke patients, School of Medicine scientists identified two genes associated with recovery. Both are involved in regulating neuronal excitability, suggesting that targeting overstimulated neurons may help promote recovery in the first 24 hours after stroke.
United States South Korea Costa Rica Laura Heitsch Barbara Burton Dennis Choi
Source: wustl.edu

Mechanical clot removal may be effective and lead to better outcomes for stroke patients

Stroke patients previously considered unlikely to survive without severe disability may regain far more function if the blood clots (which cause an ischemic stroke) are mechanically removed in addition to standard medical therapy, according to preliminary late-breaking research presented today at the American Stroke Association's International Stroke Conference 2022, a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health, held in person in ...
United States Takeshi Morimoto Shinichi Yoshimura Emily Henderson American Heart Association Hyogo College Of Medicine

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