Structural Bioinformatics News Today

Two bioactive, natural-derived compounds, which show activity at the GLP-1R site, may be orally administered with fewer side effects than their pharmaceutical counterparts.

Two plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-based study, the European Congress on Obesity (ECO 2024) (Venice 12-15 May), will hear.

Researchers have identified two plants that could offer the same weight loss results as Ozempic or Wegovy. The plant extracts mimic the hormone response that affects your eating habits.

Washington University is looking to expand its number of active learning classrooms to meet growing demand for class spaces that facilitate collaboration. Active learning classrooms often include movable seating for group work, whiteboards for brainstorming, and digital screens for students to project their work. WashU currently has nine of these classrooms on the Danforth campus, and faculty and administrators are looking to add more of these rooms in the years to come.

Charlotte Deane MBE is currently Professor of Structural Bioinformatics at the University of Oxford and Chief AI Officer at Exscientia plc. She is also a co-director of the Systems Approaches to Biomedical Research Centre for Doctoral Training which

Charlie Bowden reports on the appointment of Professor Charlotte Deane as the new Executive Chair of the EPSRC by Michelle Donelan.

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

Scientists at IRB Barcelona, ​​have developed the Bioteque, a computational tool to harmonize, integrate and simplify biological data.

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.