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"Hidden Glutathione Transferases in the Human Genome" by Aaron J. Oakley

With the development of accurate protein structure prediction algorithms, artificial intelligence (AI) has emerged as a powerful tool in the field of structural biology. AI-based algorithms have been used to analyze large amounts of protein sequence data including the human proteome, complementing experimental structure data found in resources such as the Protein Data Bank. The EBI AlphaFold Protein Structure Database (for example) contains over 230 million structures. In this study, these data ...
Protein Data Bank Protein Data Fold Protein Structure Database Eukaryotic Elongation Factor 1 Ailed Axon Connections Homolog Anglioside Induced Differentiation Associated Protein
Source: uow.edu.au

Identifying Elusive Post-Translational Modifications

Post-translational modifications (PTMs) provide a rapid mechanism that enables protein phenotypic diversity so that proteins can react to external and internal disturbances and regulate cellular activity. This Biotech Brief discusses tools and methods that are employed in detecting these sub-stoichiometric and elusive protein modifiers, including mass spectrometry, antibody, artificial intelligence, ubiquitin-clipping, and specific uncaging-assisted biotinylation-based approaches. The article al...
Claire Eyers Cristina Martin Granados Nucleic Acids Research Opin Genet Structure Database Acids Research

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