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Major trial finds apixaban reduces stroke risk in patients with device-detected atrial fibrillation

The widely available blood thinner apixaban substantially reduced stroke in at-risk patients with a type of atrial fibrillation only detectable by a pacemaker or other implanted cardiac electronic device, a global study has found.
United States Bristol Myers Squibb Renato Lopes Stuart Connolly Jeff Healey Population Health Research Institute

ANNEXA-I: Andexanet Alfa Shows Efficacy, Safety for Factor Xa Reversal in Acute ICH

The phase 4 ANNEXA-I trial was stopped early after showing superior hemostatic efficacy and the capability to limit potentially life-threatening intracerebral hemorrhage (ICH) compared with usual care in patients taking oral factor Xa (FXa) inhibitors.
Stuart Connolly World Stroke Congress A National Institutes Of Health Stroke Scale National Institutes Health Stroke Scale Intracerebral Hemorrhage
Source: ajmc.com

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