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Dual-antiplatelet therapy should remain the standard strategy for PCI even in the drug-eluting stent era

Prasugrel monotherapy after percutaneous coronary intervention (PCI) with drug-eluting stents is not superior to dual-antiplatelet therapy (DAPT) for major bleeding but is non-inferior for cardiovascular events in patients with acute coronary syndrome (ACS) or high bleeding risk (HBR), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.
Megan Craig Masahiro Natsuaki Academic Research Consortium Saga University Hot Line Bleeding Academic Research Consortium

Switching to NOACs in frail elderly patients with atrial fibrillation increases bleeding risk

Switching vitamin K antagonist (VKA) treatment to a non-vitamin K antagonist oral anticoagulant (NOAC) in frail elderly patients with atrial fibrillation is associated with more bleeding complications compared to continuing VKA treatment.
Linda Joosten Lily Ramsey Health Sciences University Medical Center Utrecht Julius Center Utrecht University

Middle-aged adults with cluster of unhealthy traits have heart attacks and strokes two years earlier

Middle-aged adults with three or more unhealthy traits including slightly high waist circumference, blood pressure, cholesterol and glucose have heart attacks and strokes two years earlier than their peers, according to research presented at ESC Congress 2023.
Lily Ramsey Study Author County Hospital Heart Attack Blood Pressure Cardiovascular Disease

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