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Study Finds Associations Between T Cell Diversity in Peripheral Blood and Patient Age, Stage of Breast Cancer Development

Researchers at Dana-Farber Cancer Institute found that the diversity of T cells in peripheral blood declines with age in patients with breast cancer and, in younger patients, is lower in those diagnosed with metastatic disease than with ductal carcinoma in situ.
United States Susang Komen Jun Nishida Kornelia Polyak Simona Cristea Franziska Michor

Chemoautotrophic production of gaseous hydrocarbons, bioplastics and osmolytes by a novel Halomonas species | Biotechnology for Biofuels and Bioproducts

Production of relatively low value, bulk commodity chemicals and fuels by microbial species requires a step-change in approach to decrease the capital and operational costs associated with scaled fermentation. The utilisation of the robust and halophilic industrial host organisms of the genus Halomonas could dramatically decrease biomanufacturing costs owing to their ability to grow in seawater, using waste biogenic feedstocks, under non-sterile conditions. We describe the isolation of Halomonas...
United Kingdom East Sussex United States Takara Bio Formedium Norfolk Pacific Biosciences

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Study finds association between being breastf

This Dana-Farber Cancer Institute-led study underscores a need for research into the biological mechanisms underlying the association between being breastfed and colorectal cancer risk, including the role of the microbiome or other pathways as well as the formulation of potential risk-reducing interventions.
Chen Yuan National Institutes Of Health Nurse Health Study Dana Farber Cancer Institute Study Title Being Breastfed

Sox9 Protein Enables Molecular Time Travel That Can Lead to Colorectal Cancer

Research from Dana-Farber Cancer Institute looks at what happens before the emergence of mutations that interrupt cellular differentiation in colorectal cancer and finds not only evidence of fetal reprogramming that can initiate cancer, but also a protein, Sox9, that fuels that reprogramming.
Matthewb Yurgelun Pratyusha Bala Nilays Sethi Williamc Hahn Jonathanp Rennhack Daulet Aitymbayev

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