Surface Protein News Today

Group A Streptococcus (GAS) M and M-like proteins are essential virulence factors and represent the primary epidemiological marker of this pathogen. Protein sequences encoding 1054 M, Mrp and Enn proteins, from 1668 GAS genomes, were analysed by SplitsTree4, partitioning around medoids and co-occurrence. The splits network and groups-based analysis of all M and M-like proteins revealed four large protein groupings, with multiple evolutionary histories as represented by multiple edges for most sp...

Johnson&johnson remain very good at doing that. you cant expect this kind of vaccine also to be highly effective against highly asymptomatic, thats good for the rotovirus or flu vaccine. you can get control of this infection by just having protection against moderate severe critical disease. so i think when people are holding up the bar of trying to get protection against asymptomatic or mildly symptomatic, thats too high a bar. i think we are scaring ours unnecessarily. >> is the answer at some...