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June 24, 2023
Renal denervation lowered blood pressure out to 36 months, regardless of baseline antihypertensive class combinations and polypharmacy burden, according to an analysis of the Global SYMPLICITY Registry DEFINE.At 36 months, 31% of participants decreased the number of antihypertensive drug classes, according to the study published in Hypertension.
January 31, 2023
The new analysis has several limitations, but Deepak Bhatt says it provides reassurances about the durability of the procedure.
September 20, 2022
Although interest in renal denervation in hypertension fell off after disappointing results from the 2014 trial, a new, longer-term analysis argues the treatment may have worked after all.
September 19, 2022
Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months.
September 19, 2022
Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months.
September 19, 2022
Plus, an apparent magnification of effect in SYMPLICITY HTN-3
September 18, 2022
BOSTON — Radiofrequency renal denervation for uncontrolled hypertension appeared to demonstrate durable BP reduction out to 3 years in the setting of maximal antihypertensive therapy, a speaker reported.The results of the long-term and final follow-up of the SYMPLICITY HTN-3 trial of radiofrequency renal denervation for resistant hypertension using a first-generation catheter (Symplicity
May 17, 2022
A taste of clinical outcomes data when a randomized trial is unlikely