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Emerging from Stealth Mode, Gene Editing Startup Prime Medicine Raises $315M

Emerging from Stealth Mode, Gene Editing Startup Prime Medicine Raises $315M July 14, 2021 Source: CIPhotos/Getty Images Prime Medicine, whose “search and replace” approach to gene editing underpins the second genome editing technology to be commercialized by the lab of David R. Liu, Ph.D., and colleagues, said today it has completed $315 million in financing, ending nearly a year of operation in stealth mode. The financing consists of a $115 million Series A round and a $200 million serie...
Davidr Liu Keith Joung Andrew Anzalone Keith Gottesdiener Feng Zhang Regeneron Pharmaceuticals

First Positive Data of In Vivo CRISPR-Based Genome Editing in Humans Reported

First Positive Data of In Vivo CRISPR-Based Genome Editing in Humans Reported June 28, 2021 A team of researchers based in the U.S., the U.K., and New Zealand from Intellia Therapeutics, Regeneron Pharmaceuticals, and clinical partners showed in a study that the companies’ lead in vivo genome editing candidate NTLA-2001 generated a dose-dependent sustained reduction of protein linked to transthyretin (ATTR) amyloidosis following a single dose in six patients living with hereditary transthyre...
New Zealand John Evans Davidr Liu Georged Yancopoulos Mani Foroohar Maury Raycroft

UNCTW: Trends in Financing Far-Right Violent Extremism - World Jewish Congress

In collaboration with the Permanent Mission of the Federal Republic of Germany to the United Nations and Global Project Against Hate and Extremism, the World Jewish Congress is organizing a virtual event entitled “Trends in Financing Far-Right Violent Extremism” on 28 June. The event will explore the confluence of the coronavirus pandemic and the financing of far-right violent extremism, in particular discussing the influence of new technologies and online capabilities such ...
United States Amber Weinber Karim Zidan Bernd Heinze Collin Almquist Cynthia Miller Idriss

Getting life-changing technologies to the poor

A setting sun used to mean that Ruby Kumari had to close the doors to her home-made sewing school in Parsa, a village in the eastern Indian state of Bihar. But the arrival of solar-powered minigrids in 2019 allowed her to stay open after sundown and offer additional classes, more than doubling enrolment to 80. Access to affordable, reliable power also meant she could switch from manual to electric sewing machines, helping her transform her skills into a new business activity in 2020 when the COV...
Shamikan Sirimanne Ruby Kumari Alfred Watkins Praveer Sinha Institute For Transformative Technologies Global Solutions Summit
Source: unctad.org

Genetic base editing treats sickle cell disease in mice

Broad Institute of MIT and Harvard Sickle cell disease (SCD) is the most common deadly genetic disorder, affecting more than 300,000 newborns worldwide each year. It leads to chronic pain, organ failure, and early death in patients. A team led by researchers at the Broad Institute of MIT and Harvard and St. Jude Children’s Research Hospital has now demonstrated a base editing approach that efficiently corrects the mutation underlying SCD in patient blood stem cells and in mice. This gene edit...
David Liu Gregory Newby Kaitly Woodard Mitchell Weiss Broad Institute Harvard University

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Connecting enhancer variants, genes, and disease; synthetic spike binders; measuring tumors' cellular mix; and more

Posted April 9th, 2021 for Broad Institute Welcome to the April 9, 2021 installment of Research Roundup , a recurring snapshot of recent studies published by scientists at the Broad Institute and their collaborators. Enhancing V2F maps GWASs have yielded thousands of genetic variants linked to disease. To help figure out the function of many of these variants, Joseph Nasser (now at Caltech), Drew Bergman, Charles Fulco (now at Bristol Myers Squibb), Philine Guckelberger (now at...
Joseph Nasser Wendy Garrett Harvard Chan Microbiome Curtis Huttenhower Stefan Dentro Guoping Feng

Key Global CX Customer Perspectives, 2021 Report

Key Global CX Customer Perspectives, 2021 Report News provided by Share this article Share this article ResearchAndMarkets.coms offering. This studys overall objective is to measure the current use and future decision-making behavior toward information technology (IT) and telecommunications across industries, regions, and business sizes. Industries include insurance and agriculture/food and beverages, banking/finance/insurance, education, energy and utilities, government, healthcare, high tech,...
Laura Wood Big Data Solutions Top Transformative Digital Solutions Used Ai Features Capabilities To Enhance Enterprise Communications Office Hours Call Research Methodology

Pairwise Raises $90 Million to Bring New Varieties of Fruits and Vegetables to Market

Press release content from Business Wire. The AP news staff was not involved in its creation. Pairwise Raises $90 Million to Bring New Varieties of Fruits and Vegetables to Market February 3, 2021 GMT DURHAM, N.C.--(BUSINESS WIRE)--Feb 3, 2021-- Pairwise announced the closing of its $90 million Series B funding round, signaling a new frontier in healthy, sustainable food innovation. Funding for the round was led by Pontifax Global Food and Agriculture Technology Fund (Pontifax AgTech), a pionee...
United States North Carolina Massachusetts Institute Of Technology Harvard University Santa Monica Laura Mccarthy
Source: apnews.com

Breakthrough Study Supports Genetic Editing as a Potential Treatment for Rare Rapid-Aging Disease Progeria

Share this article PEABODY, Mass., Jan. 6, 2021 /PRNewswire/ --  The Progeria Research Foundation (PRF) announced today the publication of a breakthrough preclinical mouse study in the journal Nature, demonstrating the substantial effect of genetic editing in directly reversing the mutation that causes Hutchinson-Gilford Progeria Syndrome (HGPS, or Progeria). Scientists at Broad Institute, the National Institutes of Health (NIH), PRF and others contributed to this ground-breaking study, indic...
United Kingdom David Liu Francis Collins Sam Berns Leslie Gordon Jonathan Brown

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