Breakthrough in β-lactam synthesis using nick
Researchers at the Institute for Basic Science (IBS) in South Korea have made a significant breakthrough in the field of asymmetric synthesis of β-lactams, which are prominent in bioactive compounds. Their innovative approach employs nickel and hydrocarbon sources that are abundant on Earth to access value-added β-lactam products. The employment of nickel-hydride catalysis and alkenyl dioxazolone derivatives gives rise to the selective formation of four-membered lactam products. This developme...
Institute For Basic Science Method Of Research Catalytic Hydrocarbon Functionalizations Basic Science Alkenes Enabling Asymmetric Synthesis Transposed Nih
Source: eurekalert.org