1. This randomised control trial demonstrated that a standardised and manualised intervention in primary care showed a sustained reduction in lower urinary tract symptoms (LUTS) in men at 12 months, as assessed through the International Prostate Symptom Score (IPSS). 2. The mean IPSS difference between the intervention and control arm of −1.81 points, while statistically
Acupuncture vs Massage for Pain in Patients Living With Advanced Cancer: The IMPACT Randomized Clinical Trial 1. This randomized clinical trial found that over a 26-week period, both accupuncture and massage effectively reduced pain and improved fatigue, insomnia, and quality of life among patients living with advanced cancer. 2. There was no significant difference between
Objective To determine whether a standardised and manualised care intervention in men in primary care could achieve superior improvement of lower urinary tract symptoms (LUTS) compared with usual care.
Design Cluster randomised controlled trial.
Setting 30 National Health Service general practice sites in England.
Participants Sites were randomised 1:1 to the intervention and control arms. 1077 men (≥18 years) with bothersome LUTS recruited between June 2018 and August 2019: 524 were assigned to the intervention arm (n=17 sites) and 553 were assigned to the usual care arm (n=13 sites).
Intervention Standardised information booklet developed with patient and expert input, providing guidance on conservative and lifestyle interventions for LUTS in men. After assessment of urinary symptoms (manualised element), general practice nurses and healthcare assistants or research nurses directed participants to relevant sections of the manual and provided contact over 12 weeks to assist with