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The impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome

Researchers from the United Kingdom evaluated the use of a high-sensitivity assay to measure cardiac troponin I and its impact on myocardial infarction (MI) risk or other long-term outcomes such as death at five years in individuals with suspected acute coronary syndrome.
United Kingdom Universal Definition Myocardial Infarction High Sensitivity Troponin Acute Coronary Syndrome Myocardial Infarction

Implementation of a high sensitivity cardiac troponin I assay and risk of myocardial infarction or death at five years: observational analysis of a stepped wedge, cluster randomised controlled trial

Objective To evaluate the impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome. Design Secondary observational analysis of a stepped wedge, cluster randomised controlled trial. Setting 10 secondary and tertiary care centres in Scotland, UK. Participants 48โ€‰282 consecutive patients with suspected acute coronary syndrome. Myocardial injury was defined as any high sensitivity assay result for cardiac tropon...
United Kingdom City Of Glasgow City Davida Mcallister Imran Sadat Frank Finlay
Source: bmj.com

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The diagnosis of heart failure is more often

The diagnosis of heart failure is usually missed, denying patients treatments that could improve wellbeing and reduce mortality. Thatโ€™s the finding from a late breaking science presentation today at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC). โ€œFor patients with heart failure, lifestyle advice, medicines and devices can improve symptoms, reduce morbidity and prolong life but this requires someone to recognise and diagnose the condition,โ€ said prin...
United Kingdom Glasgow City Czech Republic John Cleland Heart Failure Association European Society Of Cardiology

Application of a sex-specific GRACE score in practice

We wish to congratulate Florian A Wenzl and colleagues1 for their important analysis and update of the Global Registry of Acute Coronary Events (GRACE) score to address observed differences in the prediction of in-hospital mortality following non-ST-segment elevation acute coronary syndromes between women and men. If this state-of-the-art prediction model is to reduce sex inequalities in care, then additional information is needed to ensure the GRACE 3.0 score is consistently applied in practice...
United Kingdom Coll Cardiol Siemens Healthineers Floriana Wenzl Elsevier Ltd Global Registry

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