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Application of a sex-specific GRACE score in practice – Authors' reply

We thank Dorien M Kimenai and Nicholas L Mills for their interest in our Article.1 Indeed, sex-specific diagnostic thresholds of troponin were introduced into the Universal Definition of Myocardial Infarction in 2012 during the recruitment period of our study and have led to increased diagnostic sensitivity in the decade since.2
United States United Kingdom Northern Ireland Daiichi Sankyo Dorienm Kimenai Boehringer Ingelheim

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Universal Definition of Heart Failure Proposed

email article An international committee proposed a universal definition for heart failure (HF) and two standard classifications that go beyond reduced and preserved left ventricular ejection fraction (LVEF). "HF is a clinical syndrome with symptoms and or signs caused by a structural and or functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and or objective evidence of pulmonary or systemic congestion," according to the consensus document from the Hear...
United States New Zealand Baylor College Of Medicine Nicole Lou Biykem Bozkurt Heart Failure Society Of America

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