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Moffitt Cancer Center researchers identify hidden target of ROS1 inhibitor lorlatinib

October 16, 2023

Targeted cancer drugs are widely used because of their ability to inhibit specific proteins involved in cancer development with fewer side effects compared to chemotherapy drugs.

Danielle Ellis Uwe Rix Department Of Defense Lung Cancer Research Program Department Of Drug Discovery At Moffitt National Cancer Institute Moffitt Lung Cancer Center

Source: news-medical.net

Research: Fibroblasts connected to cancer increase drug sensitivity

August 21, 2022

Despite some studies suggesting that these fibroblasts may also make cancer cells more sensitive to therapy, cancer-associated fibroblasts in the tumour environment have typically been linked to tumour progression and resistance to therapy.

Uwe Rix Department Of Drug Discovery At Moffitt Moffitt Cancer Center Science Signaling Lily Remsing Rix Drug Discovery

Source: webindia123.com

Researchers find cancer-related fibroblasts induce drug sensitivity

August 17, 2022

Cancer-associated fibroblasts in the tumour environment have typically been associated with tumour progression and resistance to therapy, despite some studies suggesting that these fibroblasts may also sensitize cancer cells to therapy.