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Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.
United States Emilia Javorsky Lily Ramsey Robert Mannix Sean Hall Amanda Jiang

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule.
United States Baden Wüberg Constance Cepko Ninning Liu Donald Ingber Sinem Saka

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