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Cardiac Antigen Identified as Mechanism for Heart Complication

(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%. Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation. The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism...
United States Wouter Meijers Yueli Zhang Ayaka Sugiura Javid Moslehi Xiaopeng Sun

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