January 25, 2021
Even in asymptomatic patients with aortic stenosis (AS) and minimal signs of cardiac damage, early treatment with surgery provides a long-term survival benefit over conservative management, a new analysis of the RECOVERY trial shows.
Researchers assessing the prognostic value of a disease classification tool which relies on the degree of damage to stage AS found much lower rates of CV or all-cause death at 8 years for patients in the lower stages compared with higher stages. But surgery across all disease categories still offered benefits over conservative management, they said.
“Because the risk-benefit ratio of early elective AVR over conservative management in asymptomatic AS may differ according to stages of cardiac damage, further prospective studies will be necessary to facilitate the identification of patients that may benefit from early intervention,” write Sung-Ji Park, MD, PhD (Asan Medical Center, Seoul, Korea), and colleagues in a research letter
January 25, 2021
Two new reviews throw cold water on the health promises of dietary supplements, particularly vitamin D and calcium, as well others, with experts concluding their intake should be avoided or discouraged for the prevention of cardiovascular disease.
In the first review, published January 25, 2021, in the
Journal of the American College of Cardiology, Erin Michos, MD (Johns Hopkins University School of Medicine, Baltimore, MD), and colleagues state that supplemental vitamin D for cardiovascular health should be discouraged because there is no solid evidence, including from recent randomized controlled trials, that it provides any benefit for cardiovascular risk reduction.
“The pendulum has now swung, and the sun has set for vitamin D, at least for heart health,” said Michos. While vitamin D doesn’t appear to cause any harm, people would be better off getting their fill through a healthy diet and moderate sunlight exposure, she said.
January 25, 2021
For patients successfully resuscitated after cardiac arrest, it’s possible to predict their odds of survival by counting how many risk factors are present, data from the International Cardiac Arrest Registry (INTCAR) confirm.
Thanks to more-aggressive care, such as targeted temperature management (TTM) and coronary angiography/intervention, survival to hospital discharge for these patients has risen from around 25% to 50% in recent years, researchers say. Still, the burden of “multiple unfavorable features,” as worded in a 2015 algorithm from the American College of Cardiology (ACC) Interventional Council, can portend worse outcomes even in the face of this advanced treatment.
Exactly how many risk factors mattered, and to what extent, hadn’t previously been pinpointed.
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Icosapent Ethyl Included in the Chinese Society of Cardiology (CSC) Updated Guidelines for Primary Prevention of Cardiovascular Diseases
Icosapent Ethyl Included in the Chinese Society of Cardiology (CSC) Updated Guidelines for Primary Prevention of Cardiovascular Diseases
DUBLIN, Ireland and BRIDGEWATER, N.J., Jan. 21, 2021 Amarin Corporation plc (NASDAQ:AMRN) today announced that the Chinese Society of Cardiology (CSC) has included icosapent ethyl in its updated Guidelines for Primary Prevention of Cardiovascular Diseases for 2021 as published in the
Chinese Journal of Cardiovascular Diseases. The guideline authors include “icosapent ethyl 2 grams twice a day (as studied in REDUCE-IT