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IMAGE: Tian s research reveals a novel winner-takes-all resource competition between synthetic gene circuits within one host cell. view more
Credit: Graphic created by Xiaojun Tian/ASU.
A new process for inserting synthetic gene circuits into host cells, developed by a team of bioengineers at Arizona State University, has broad implications for improving the effectiveness of a range of disease therapies.
Synthetic biology is an interdisciplinary research field that uses engineering principles to create biological components that don t exist in the natural world. These synthetic components mimic naturally evolved organisms, but are customized to fight disease, including cancer.
A paper recently published in
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IMAGE: From left to right, Prof. Sang Woo Seo, Dr. Jina Yang, Mr. Yong Hee Han view more
Credit: Seoul National University
On Feb 5th, Seoul National University, College of Engineering (Dean Kookheon Char) announced that Professor Sang Woo Seo s research team (Dr. Jina Yang and Mr. Yong Hee Han (graduate student)) at School of Chemical and Biological Engineering has developed a synthetic protein quality control system to enhance full-length translation in bacteria. This technology is expected to increase the efficiency of the production of biopharmaceuticals, industrial enzymes, and bio-based chemicals.
Recombinant proteins are used in various industrial fields from protein drugs such as insulin to industrial proteins such as laundry detergents. Since proteins can perform their functions only with full-length and proper 3D structure, recombinant protein production using microbial cell factories requires several protein purification steps. To enhance the yield
Researchers at Geisinger have found that a computer algorithm developed using echocardiogram videos of the heart can predict mortality within a year.
The algorithm an example of what is known as machine learning, or artificial intelligence (AI) outperformed other clinically used predictors, including pooled cohort equations and the Seattle Heart Failure score.
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PITTSBURGH (Feb. 8, 2021) . In this digital age, where the internet accelerates technological development, there has been a surge of scientific innovation designed to improve the quality of life for patients in need. However, there are physical, cognitive, and sensory issues that are often overlooked during the process, resulting in poor design for a particular user group -adults aged 65 and older. According to the U.S. Census Bureau, this group will comprise more than 20 percent of the U.S. population starting in 2030.
Highlighting the importance for safety and efficacy, the U.S. Federal Drug Administration has made incorporating human factors a priority for device approval which can significantly impact the road to commercialization, leaving many researchers stuck in the design phase. Unfortunately, many of these technologies and interventions struggle to advance to commercialization.
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IMAGE: A rearrangement event in a monodisperse foam. Note how bubbles move in the same direction along the same row, or in exactly the opposite direction in adjacent rows over long. view more
Credit: Tokyo Metropolitan University
Tokyo, Japan - Researchers from Tokyo Metropolitan University studied the dynamics of foams. When a drop of water was added to a foam raft, the bubbles rearranged themselves to reach a new stable state. The team found that bubble movement was qualitatively different depending on the range of bubble sizes present. Along with analogies with soft-jammed materials, these findings may inspire the design of new foam materials for industry.