Scientists at EPFL have discovered that Alzheimer s-like protein aggregates underly the muscle deterioration seen in aging. But the aggregates can be reversed by boosting the levels of nicotinamide adenine dinucleotide (NAD+), which turns on the defense systems of mitochondria in cells and restores muscle function.
Researchers at Canada s McMaster University have developed a new form of cultivated meat using a method that promises more natural flavour and texture than other alternatives to traditional meat from animals.
E-Mail
Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood.
However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs.
Published in We found that scleroderma inflammation dramatically increases CD38, an enzyme that normally breaks down a metabolic nutrient, NAD+. When NAD+ levels decrease, tissue injury becomes chronic and progresses to scar formation rather than to healthy repair, says study author John Varga, M.D., division chief of rheumatology at Michigan Medicine.
According to the study, treatments that prevented NAD+ reduction in the mice, whether by boosting the levels of the nutrient genetically or pharmacologically, prevented scarring in the skin, lungs and abdominal wall.
E-Mail
Your food intake patterns are partly under genetic control, according to the latest research from researchers at King s College London, published today in the journal
Twin Research and Human Genetics.
Researchers can study the quality of an individual s typical diet by using a type of analysis called dietary indices . Researchers use dietary indices to understand what foods someone eats and the nutrients provided, compared with recommended guidelines.
The team analysed food questionnaire responses from 2,590 twins, using nine commonly used dietary indices. The researchers studied the degree of similarity among identical twins - who share 100% of their genes - compared with non-identical twins, who share 50% of their genes.
E-Mail
IMAGE: MRI photos illustrate the green MED diet effect on hepatic fat loss A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver. view more
Credit: Gut 2021
BEER-SHEVA, Israel.January 18, 2021 - A green Mediterranean (MED) diet reduces intrahepatic fat more than other healthy diets and cuts non-alcoholic fatty liver disease (NAFLD) in half, according to a long-term clinical intervention trial led by Ben-Gurion University of the Negev researchers and a team of international colleagues.
The findings were published in
Gut, a leading international journal focused on gastroenterology and hepatology. Our research team and other groups over the past 20 years have proven through rigorous randomized long-term trials that the Mediterranean diet is the healthiest, says lead researcher Prof. Iris Shai, an epidemiologist in the BGU School of Public Health who is also an adjunct professor at the Harv