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Los Angeles (April 1, 2021) Overweight children and adolescents receiving chemotherapy for treatment of leukemia are less successful battling the disease compared to their lean peers. Now, research conducted at the Cancer and Blood Disease Institute at Children s Hospital Los Angeles indicates that modest changes in diet and exercise can greatly increase survival in youth treated for acute lymphoblastic leukemia (ALL), the most common childhood cancer. To our knowledge, this is the first study to show that by limiting calories and increasing exercise we can make chemotherapy more effective in eliminating leukemia cells within the first month of therapy, decreasing the chances of disease relapse in children and adolescents, says Principal Investigator Etan Orgel, MD, MS, Director of the Medical Supportive Care Service in the Cancer and Blood Disease Institute at Children s Hospital Los Angeles. The study is published in the American Society of Hematology s journal
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Many bacteria swim towards nutrients by rotating the helix-shaped flagella attached to their bodies. As they move, the cells can either run in a straight line, or tumble by varying the rotational directions of their flagella, causing their paths to randomly change course. Through a process named chemotaxis, bacteria can decrease their rate of tumbling at higher concentrations of nutrients, while maintaining their swimming speeds. In more hospitable environments like the gut, this helps them to seek out nutrients more easily. However, in more nutrient-sparse environments, some species of bacteria will also perform chemokinesis : increasing their swim speeds as nutrient concentrations increase, without changing their tumbling rates. Through new research published in
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Credit: Photo: C. Schranner / Leibniz-LSB@TUM
A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time. Similar to zip codes, the codes ensure that the sensor proteins are targeted from inside the cell to the cell surface, where they begin their work as odorant detectors. The new findings could contribute to the development of novel test systems with which the odorant profiles of foods can be analyzed in a high-throughput process and thus could be better controlled.
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IMAGE: Article published by Brazilian researchers in Sports Medicine presents a systematic review of scientific studies on the topic view more
Credit: Laboratório de Pesquisa em Movimento Humano/UNESP
Brazilian researchers have published a systematic review of the scientific literature showing that some warm-up strategies such as dynamic stretching can effectively prepare soccer players to maintain kicking accuracy, whereas intense physical exercises have a negative effect on the velocity of the ball when kicked, and consumption of carbohydrate beverages during a match can enable players to maintain adequate kicking performance in the concluding moments of prolonged physical exercise such as a sudden-death playoff.
Too much sugar is unhealthy - that we know, but it s not just down to the many calories. Even moderate amounts of added fructose and sucrose double the body s own fat production in the liver, researchers from the University of Zurich and the University Hospital Zurich have shown. In the long term, this contributes to the development of diabetes or a fatty liver.