Credit: The Wistar Institute
PHILADELPHIA (March 12, 2021) Scientists at The Wistar Institute identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells. These findings, reported in
Nature Communications, reveal an additional oncogenic function of ADAR1 and reaffirm its potential as a therapeutic target in cancer.
The lab of Kazuko Nishikura, Ph.D., professor in the Gene Expression & Regulation Program of The Wistar Institute Cancer Center, was one of the first to discover ADAR1 in mammalian cells and to characterize the process of RNA editing and its multiple functions in the cell.
Despite being discovered almost 300 ago, photosynthesis still holds many unanswered questions for science, particularly the way that proteins organise themselves to convert sunlight into chemical energy and at the same time, protect plants from too much sunlight.
Now a collaboration between researchers at the University of Leeds and Kobe University in Japan is developing a novel approach to the investigation of photosynthesis.
Hokkaido University
“I first took notice of this trend during my research on the disaster volunteers of the 2011 Tohoku earthquake and tsunami. There was a significant number of volunteers from urban areas who permanently settled down in the Tohoku area and started their own business,” explained Klien.
According to her, rural areas in general have been associated with rustic, bleak images. In the aging society of Japan, rural areas have a high number of senior citizens. This entails more problems: vacant houses, tradition discontinuity, etc. Hence, the general expectation is that younger people make attempts to escape from the countryside and seek bigger opportunities in urban and industrial regions.
Speaking whilst infected with COVID-19 may cause it to spread
Thought LeadersDr. Keiko IshiiAssistant ProfessorAoyama Gakuin University
In this interview, News-Medical speaks to Dr. Keiko Ishii about her research efforts during the COVID-19 pandemic and how speaking whilst infected can cause the virus to spread, and why wearing masks is so important.
What provoked your research efforts into the COVID-19 pandemic?
Our research started when Professor Onishi of Yamano College of Aesthetics in Japan asked me for an image that would help to prevent the spread of infections at a beauty salon.
It is natural to be careful about sneezing and coughing in people who have symptoms. However, it has been identified that coronavirus can also be asymptomatic and that these people can be infectious, which may cause explosive spread.
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