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High expression of cell death genes may increase risk of early death from lung cancer

High expression of cell death genes may increase risk of early death from lung cancer Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report. Also seemingly paradoxically, patients with high expression of this 21-gene cell death signature the researchers have identified, have indicators that their immune system is attacking the cancer, like higher levels of cytotoxic T cells, which typically kill cancer. But they also have high levels of molecules that can suppress those T cells, helping transform them into dysfunctional, exhausted T cells, they report in the journal

High expression of cell death genes associated with early death from lung cancer

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