Signs that you are ready to start your own business
Are you thinking about starting your own business? Maybe you have always dreamt of having a role in your own company, but you just don’t know where to start. Either way, being your own boss certainly is an exciting experience and if you push yourself then you may even find that you are able to get a higher level of job security as well.
You’re Passionate about your New Venture
Passion is quite often overhyped. It’s really not enough on its own but at the end of the day it is essential. You have to make sure that you have something that you are excited about starting rather than it boiling down to being frustrated with your current job. If you spend too much time focusing on how bad your job is now and you think that the only way you can change it would be by starting a new business then this won’t be doing you any favours, in fact, it may even end up putting your financial situation in jeopardy.
1Division of Cardiovascular Disease, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States
2Molecular and Cellular Pathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL, United States
3Department of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL, United States
4Center for Translational Medicine, Temple University, Philadelphia, PA, United States
Background: Endothelial cells (ECs) play a critical role in the maintenance of vascular homeostasis and in heart function. It was shown that activated fibroblast-derived exosomes impair cardiomyocyte function in hypertrophic heart, but their effect on ECs is not yet clear. Thus, we hypothesized that activated cardiac fibroblast-derived exosomes (FB-Exo) mediate EC dysfunction, and therefore modulation of FB-exosomal contents may improve endothelial function.
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