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Caption: Researchers employed a software system called Geomic to integrate vast amounts of gene expression data from the brains of mice modeling Huntington s disease. By comparing multidimensional mathematical surfaces plotted from the data, they were able to gain new insights into how gene expression differs in the disease based on many dimensions such as time, cell type and the extent of mutation in the huntingtin gene. Credits: Image: Lucile Megret/Sorbonne Universite
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Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington’s disease may progress to advanced stages more because of a degradation of the cells’ health maintenance systems than because of increased damage from the disease pathology itself.
UCLA In the News February 23, 2021 ucla.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ucla.edu Daily Mail and Mail on Sunday newspapers.