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UW Medicine begins clinical trial of experimental Novavax COVID-19 vaccine

OLYMPIA, WA - A Phase 3 clinical trial in volunteers will help determine the efficacy of a Novavax vaccine candidate in protecting against SARS-CoV-2, the coronavirus responsible for COVID-19. UW Medicine researchers are starting to enroll volunteers for this investigational vaccine clinical trial.   UW Medicine s site for enrolling participants will be the Virology Research Clinic at Harborview Medical Center’s Ninth and Jefferson Building in Seattle. Up to 1,000 volunteers will be enrolled.  UW Medicine researchers will make the vaccine trials accessible and equitable for populations that have been disproportionately impacted by the COVID-19 pandemic. This effort will include deploying mobile sites at other locations in Washington state. 

Researchers find cheap, easy way to disinfect N95 masks

Getty Images Once exposed to methylene blue, the solution, when exposed to bright light, continues to inactivate the coronavirus days. A small amount of methylene blue, with a large dose of sunlight or bright light, is all that’s needed to inactivate the coronavirus on N95 masks. These are the gold standard for masks among health-care workers. This method also works on some other personal protection equipment, or PPE, so needed by medical workers, a new study released December 11 concluded. The findings were part of a 6-month-long DeMaND study (Development of Methods for Mask and N95 Decontamination), which involves researchers from the Centers for Disease Control and Prevention, from the World Health Organization, and from 12 institutions, including the University of Washington School of Medicine and Seattle Children’s Research Institute.

Long-term opioid use cannot treat chronic pain, has serious health consequences

Long-term opioid use cannot treat chronic pain, has serious health consequences A broken heart is often harder to heal than a broken leg. Now researchers say that a broken heart can contribute to lasting chronic pain. In a reflections column published Dec. 21 in the Annals of Family Medicine, pain experts Mark Sullivan and Jane Ballantyne at the University of Washington School of Medicine, say emotional pain and chronic physical pain are bidirectional. Painkillers, they said, ultimately make things worse. Their argument is based on new epidemiological and neuroscientific evidence, which suggests emotional pain activates many of the same limbic brain centers as physical pain. This is especially true, they said, for the most common chronic pain syndromes - back pain, headaches, and fibromyalgia.

More evidence suggesting that Covid-19 can enter the brain

Emerging evidence shows that virus proteins are able to crossover into the brain This may have dire consequences, as the proteins can be toxic to brain tissues Increasing amounts of evidence suggest that the novel coronavirus has negative effects on cognitive function, as some Covid-19 patients have shown symptoms indicating that their cognitive function has been affected. Health24 previously reported on a study showing that the virus enters the brain through nerve cells in the olfactory mucosa (the cells that contain receptors for taste and smell). Now, a newer study, also assessing the cognitive effects of the virus, looks at how it enters our brains.

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