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Researchers discover new binding sites for active agents on cell cytoskeleton
Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute PSI have discovered new binding sites for active agents - against cancer, for example - on a vital protein of the cell cytoskeleton. Eleven of the sites hadn t been known before. The study appears today in the journal
Angewandte Chemie International Edition.
The protein tubulin is an essential building block of the so-called cell cytoskeleton. In cells, tubulin molecules arrange themselves into tube-like structures, the microtubule filaments. These give cells their shape, aid in transporting proteins and larger cellular components, and play a crucial role in cell division.
Apr 29, 2021
Advanced robotics, combined with artificial intelligence and machine learning technology, could transform spinal surgery safety, costs, and recovery for millions of patients worldwide over the next decade.
That’s the word from Dr Michael Steinmetz, chairman of the Department of Neurosurgery and Director of the Centre for Spine Health in the Neurological Institute, Cleveland Clinic, who adds: “We have the robotics, and artificial intelligence and machine learning technology now to transform spinal surgery. Robotics can support spinal surgeons to optimize surgical costs, safety, and patient recovery. Over the next decade, robotics could lead a breakthrough in even more efficient and safer spinal surgeries.”