Updated Jan 11, 2021 | 11:01 IST
The study stated that the testing platform can identify the presence of two COVID-19 antibodies, spike S1 protein and receptor-binding domain (RBD), from a very small drop of blood. No more waiting! A new COVID testing platform can detect antibodies within seconds | Photo Credit: iStock Images
Key Highlights
Testing for COVID-19 has been touted as one of the best ways to curb the spread of the infection
Tests such as RT-PCR tests and antibody tests can take a few hours for results
A new testing platform can now detect COVID antibodies within seconds, reducing the turnaround time for such tests
Rapid Antibody Testing For COVID-19 by Pooja Shete on January 11, 2021 at 12:43 PM
An advanced nanomaterial-based biosensing platform has been found by the researchers that detects antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic within seconds. Additional to testing, this platform will help to quantify patient immunological response to the new vaccines with precision.
The study conducted by researchers at Carnegie Mellon University in collaboration with University of Pittsburgh (Pitt) and the UPMC is published in the journal
Advanced Materials.
The testing platform identified the presence of two virus antibodies- spike S1 protein and receptor binding domain (RBD), in a very small drop of blood. Antibody concentrations can also be detected in low concentrations and this detection happens through an electrochemical reaction within a handheld microfluidic device which sends results almost immediately to a simple interface o
“We utilised the latest advances in materials and manufacturing such as nanoparticle 3D printing to create a device that rapidly detects COVID-19 antibodies,” said Rahul Panat, an associate professor of mechanical engineering at Carnegie Mellon who uses specialised additive manufacturing techniques across his biomedical research.
To create the device, the team used an additive technique known as aerosol jet 3D printing. Tiny, inexpensive gold micropillar electrodes were printed at nanoscale by thermally sintering aerosol droplets together. This causes a rough, irregular surface that provides increased surface area of the micropillars and an enhanced electrochemical reaction, where antibodies can latch on to antigens coated on the electrode. The specific geometry allows the micropillars to load more proteins for detection, resulting in very accurate, quick results.
Indian-Origin scientist develops nano 3D device to detect Covid-19 virus in 15 seconds Posted by: Narsingrao Sridhar January 10, 2021
Researchers at Carnegie Mellon University have developed an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2 or the coronavirus. It also helps to assess patient immunological response to the new vaccine.
The study, published in the journal
Advanced Materials, is Carnegie Mellon’s collaboration with the University of Pittsburgh (Pitt) and the UPMC.
The testing platform identifies the presence of two of the virus’ antibodies, spike S1 protein and receptor binding domain (RBD), in a very small drop of blood (about 5 microliters). Antibody concentrations can be extremely low and still detected below one picomolar (0.15 nanograms per milliliter). This detection happens through an electrochemical reaction within a handheld microfluidic device which sends results almost immediat
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