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Researchers from Queen Mary University of London and Zhengzhou University have developed a powerful therapeutic platform that uses a modified virus for the treatment of pancreatic cancer. By using the virus in combination with other drugs, the treatment significantly extended survival in preclinical models of pancreatic cancer.
Viruses that can selectively infect and destroy cancer cells, known as oncolytic viruses, are a promising new class of therapeutics for cancer. Through various mechanisms, oncolytic viruses kill cancer cells and elicit strong anti-tumour immune responses. However, current oncolytic virotherapy is unable to produce a long-term cure in patients, and the treatment has to be delivered directly into the tumour - a route that is not feasible for deeply embedded tumours, or tumours that have spread around the body.
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The disproportionately high Covid-19 infection rates observed in Black Americans could be linked to their daily commuting patterns, according to a new study published today in the
Journal of the Royal Society Interface.
The research found that increased exposure to other ethnic groups, for example as a result of an individual s job or use of public transport, can result in the emergence of an infection gap in the population, such as the abnormally high incidence of Covid-19 recorded in Black Americans.
In some areas of the US Covid-19 incidence in Black Americans can be up to three to five times higher than would be expected based on population data. Previous studies have highlighted socio-economic factors including lower income and poorer access to healthcare facilities could play a role in this infection gap but these factors alone cannot completely explain the disproportionate impact of the pandemic on Black Americans.
Novel platform uses modified virus to combat pancreatic cancer
Researchers from Queen Mary University of London and Zhengzhou University have developed a powerful therapeutic platform that uses a modified virus for the treatment of pancreatic cancer.
By using the virus in combination with other drugs, the treatment significantly extended survival in preclinical models of pancreatic cancer.
Viruses that can selectively infect and destroy cancer cells, known as oncolytic viruses, are a promising new class of therapeutics for cancer. Through various mechanisms, oncolytic viruses kill cancer cells and elicit strong anti-tumour immune responses.
However, current oncolytic virotherapy is unable to produce a long-term cure in patients, and the treatment has to be delivered directly into the tumour - a route that is not feasible for deeply embedded tumours, or tumours that have spread around the body.
Bizarre dinosaur Spinosaurus behaved like a giant, flightless stork, study says
CNN
27th January, 2021 11:37:17
Paleontologists have long been puzzled about how the Spinosaurus a giant dinosaur and aquatic predator would have behaved.
Now, they believe it would have been less like an otter, and more like a huge, flightless stork or heron.
Rather than hunting fish in the water, the massive dinosaur would have likely caught prey out of the water from a position on the shoreline, researchers from Queen Mary University of London and the University of Maryland found in a study published Tuesday.
Spinosaurs were a group of large-bodied theropods that were bigger than both Tyrannosaurus rex and Giganotosaurus, growing to around 15 meters (49.2 feet) in length. These dinos lived during the Cretaceous period between 145.5 and 65.5 million years ago.
An international research collaboration, involving scientists from the UK, US and Spain, has shed new light on the usefulness of digital contact tracing (DCT) to control the spread of Covid-19.