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The Vaccine Was Fast Here s How to Make it Faster

The Vaccine Was Fast. Here s How to Make it Faster By Allison Shelley The most ambitious vaccine deployment in history promises to stop a pandemic that has already claimed 1.67 million lives. But what if a vaccine for COVID-19 had been available sooner, say as early as March? It s a question raised by Florian Krammer, PhD, a microbiologist at the Icahn School of Medicine at Mount Sinai in New York City. In a just-published commentary in the journal Cell, he reflects on the loss of life and says vaccines now will make a significant impact on ending the pandemic, but were needed much earlier.

Alzheimer s Disease Linked to Dysfunction Circadian Clock

Studies by a research team at Washington University School of Medicine in St. Louis indicate that a brain protein known as YKL-40 may link Alzheimer’s disease with dysfunction in circadian rhythms, suggesting that treatments that target the protein could slow the course of the disease. Their work, reported in Science Translational Medicine, found that YKL-40 is both regulated by clock genes and involved in clearing away the potentially toxic build-up of Alzheimer’s proteins in the brain. The team’s studies indicated that Alzheimer’s patients who carry a genetic variant that reduces YKL-40 levels maintain their cognitive faculties longer than those individuals without the variant.

Historic, hopeful moment arrives as COVID-19 vaccinations begin on Medical Campus | The Source

December 17, 2020 SHARE Joan Niehoff, MD, receives a vaccine against COVID-19 Dec. 17 on the Medical Campus. Health-care workers and other employees in contact with patients received vaccines from the first shipment to arrive on the Medical Campus. (Photo: Matt Miller/School of Medicine) As part of a historic effort to end the COVID-19 pandemic, health-care personnel at Washington University School of Medicine in St. Louis and BJC HealthCare have begun receiving the first doses of a vaccine against the SARS-CoV-2 virus. Almost 10,000 doses of the Pfizer vaccine will be administered in the coming weeks to School of Medicine and BJC employees who have direct contact with patients, work in patient-care areas or handle potentially infectious materials, such as nasal swab samples. Such patient-facing personnel have been prioritized by the Centers for Disease Control and Prevention (CDC) and the state of Missouri to receive the vaccine first.

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