A Look at Michigan’s largest lottery wins Friday’s winning Mega Millions makes history as third-largest lottery prize in U.S. Tags: NOVI, Mich. – When someone comes forward to claim the $1 billion Mega Millions prize, they will make history in Michigan. Hundreds of Michiganders have hit it big playing the lottery. According to the Michigan Lottery, more than 400 people have won at least $1 million each, but only a handful have at least $10 million and only six have won at least $100 million until Friday. In 2005, Mary and Ralph Stebbins won $208 million. The couple took the lump sum, which left them with a little more than $125 million before taxes.