Response to the mass killing of ring of muslims in 2017 sanctions target me a march commander in chief and several other Senior Officers former privy and president are 100. 00 to later has been arrested in the United States and faces extradition on corruption charges to later is accused of taking 20000000. 00 in bribes from Brazilian Construction Company or direct in exchange for lucrative contracts a new York Police Officer will not face charges for killing a black man he was trying to arrest the Justice Department made the announcement on cheese day 5 years after eric garner died in a chokehold so african singer and antiapartheid activist johnny clegg has dies at the age of 66. 00. Nicknamed the point 0 he was fame for blending traditional african rhythms and western music styles well thats europe today its the news continues and aljazeera after the cure revisit it. A group of women are fighting for the right to enter a cycle of hindu temple that has long been the exclusive domain of man one i want to waste investigates the battle to overcome centuries of scrimmage nation in india on aljazeera. It. Was some trick of nature these stem cells and white swan are on. Which this whole procedure is a bad joke like a bank but its more sophisticated isnt it the reality is that by importing american my cocounsel a. C. O. R. It doesnt matter that worldwide 350000000 people are affected by genetic disorders caused by faulty d. N. A. These genetic defects can lead to a variety of conditions like Cystic Fibrosis which leads to conic and also cite a long sections and at the moment the system and here i am dr Elizabeth Healy in the u. K. To see how groundbreaking developments in gene therapy could one day transform the lives of People Living with genetic disorders. Have a parallel but not marry bond on a is 16 years old and was diagnosed with Cystic Fibrosis at the age of one. Mary kay tell me from your perspective what is your day like living with Cystic Fibrosis. Arum when i asked her i guess op take my interview rises office. And then youre sitting in my inbox tears. And i asked you i know now your eyes are failing. And theyre nasty to my physio if. I do spiral a. J. And im going to go out and cheerfully in there helping me. And then often ask to do another not be lies well. There are still more passes. And then i will need face or should you have oh no so learning in our night. When mary was 1st diagnosed doctors thought she would only live until the age before. My decision i was dazed and not ready to emerge or. Unknown house turned on i thought id take the medication then of ok. Theres never a day goes by either and talk to everybody forget the whole thing you know live it up so i know its always there. Married to use me to the children to see fibrosis. To summarize if i me one of them there were no passage i want to me or on one passage im going to. So now its a question isolating condition to hear yet because i was in a special when i was not a c. S. Patient theyre all right. So i only used to send or letters to each other or. Because they couldnt me if they said they saw me fly now last night at the moment mary is not really understanding everything about c. F. She she does now know that it is life show me that she doesnt know that it cannot be kids. But things could be about to change scientists have proven for the 1st time ever that an experimental technique called gene therapy can improve the health of those with Cystic Fibrosis ive come into Central London to meet the doctors and the clinicians involved in the gene therapy trial into Cystic Fibrosis. Resting in baghdad. Adding with each. Distinct fibrosis is as you know a genetically inherited disease parents who pass those copies on to their child and they have Cystic Fibrosis during the 1st year of life most babies will experience and lung problems and those relates to the buildup of sticky mucus within the airways and that sticky mucus attracts bacterial infections and the bacteria infections become chronic and they eventually cause quite significant lung scarring in the u. K. There are around 10000 people with Cystic Fibrosis at the moment on our registry about one in 22 of us is a carrier of the mutated gene most of us wont realise and about one in 2000 babies are born with Cystic Fibrosis the genetic nature of this and other conditions mean that treatment has focused on managing the sentence as best as possible but a new and experimental technique called gene therapy replace the faulty gene with a functioning one this is the largest and the longest duration gene therapy trial using a liquid formulation for Cystic Fibrosis that has ever happened in the 116. 00 patients completed the protocol and took at least 9 doses over the course of a year and it was in that group which was defined as being the group we were going to look at that we saw a Significant Impact on lung function at the end of the year. We can thank the patients and their families in earth because without patients like mary and her mother we just couldnt have completed this trial so were really grateful. These results would not have been possible without the perseverance of scientists who spent years developing the genes and. We started this program and it started would be very easy for patients to just in pair the Gene Research and if it gets to the right area into the right cells in the lung it turned out that was much more difficult so how are you getting this healthy new gene into the areas and learn to do the job of the some teaching. For the try that has just finished it actually using a very symptomatic cure its a had it lifted but we did this we used the gene and we mixed it with this that this formed a smaller complex that complex it is then inhale it into the lungs of Cystic Fibrosis patients the dose of gene therapy that the trial participants received does not determine the correct the faulty Cystic Fibrosis d. N. A. But scientists are working on finding a longer lasting solution Clinical Trial results have been very encouraging but theyre not quite good enough to turn them into a treatment yet so we have plans for another trial where we get more there is some gene complexes and more frequently basically in addition to that we have to developed by or is said just very very efficient in getting genes into the lungs do you think use you know fires might be more efficient than using the fatty possibly using them and we certainly think so based on all the evidence we have the virus is at least 140 more effective fighting very exciting you know. These Success Stories represent a huge step forward for people. Matt did you notice any changes cheering the course of the treatment i thought i had no more injury i didnt eat well though cherry mark a. Worker was the best of my parade still going up close getting a little lot done. And how does that make you feel when you submit cheating so mean that i make sure you get to know i could die i die i could do that and i know i can damn the hype is that one day gene therapy will be approved for use and widely available to those with Cystic Fibrosis or those people that are studying and working to get this drug to work even better than it did its just pray they can get it done and they can get the funding and if it doesnt come soon enough mary shes helped other faithful if its not to be the next generation of children born with Cystic Fibrosis in a city some are. Going to begin to say i sound all year how corny mincemeat for seniors. Is that really the sermonize. Alymer back again. Things can stay there. By the age of 85 nearly hauffe of us will suffer from oxygen damage to the name which can lead to chronic pain and disability or perhaps because cartilage unlike other tissues doesnt have its own blood supply so heals very slowly and off the job when ive been here ashima japan to meet the surgeon pioneering new techniques in regenerating on the. Professor myth so old she. Is one of the worlds leading nice surgeons and a revered figure in the world we generated medicine. Professor to be here. Ok thank you. Jay tech is an enterprise focusing on Tissue Engineering and has spent over 10 years commercializing professor archies research. Associate yeah. Right nice to see how you very welcome things are back. In 1001004 my dance on paper was published by Swedish Group the swedish team had developed a way of regenerating cottage in a lab and then re injecting it in liquid form directly into the knee however there was a weak point all with their technique. In order to solve this problem started to use the very same scale for the. Yes you can imagine that. The foot would be here coming up yes if that. Meniscus has no blood supply or if injury is. A song we are the light to resect so what you can do with this Regenerative Medicine is to take the patients own cartilage from the same joint yes all the chain the confidence is essential company i see it does she engineer the cuts. And thats why were here yeah just half a gram of healthy cartilage is harvested it is then broken down with enzymes and then planted on a college in scaffold designed by professor ought to after just 4 weeks the cells will have multiplied to form a 4 square sent me to this. Surgeon then makes a template of the lesion and uses that to harvest some perry all still tissue from the shin bone. This will be the cover used to hold the new cartilage in place so this is a model of someones potentially regenerated cartilage but the beauty of it being the patients own cells here is that its not rejected you know any medicine from the viewpoint i mean you know roger reaction oh told you nasty issue is a topic today this method has an almost 90 percent success rate and is considered a leading treatment fanie cartilage d. Fax will what are the limitations of this can it be done better we need a larger scheme. That is invasive. Painful after surgery so less invasive technique is desired i have another new proceed youre using the magnetic. The goal is to devise a less invasive procedure. Much like the original idea of simply injecting the cartilage into the knee we inject saw many serious. 10000000 serious we open our scar tissue in the knee joint. The you see the injectors so you cant see if inject cells blindly into the fluid nuptial they go all over and that made scarring so youd rather just close the where there is actually enjoy the right pinpoint targeting so how did you achieve that so i decided to use small i am particle. To do that. Didnt come as stimson counterpart of that small i am part of the action and stem cells not that i am confident is then that they can be controlled that direction with a strong month then my lord thats the most in the will magnetic force. From here theres the injection thirds are attracted to the deeper the area is being channeled. By some sort of trick of nature that these stem cells like to swallow are not honest which is this whole procedure hinges on that because then you can manipulate. That solution of stem cells with a magnetic field. So not having to cut open the knee in any way you can attach those themselves to just the area where the