High profile dismissal President Donald Trump announces hes fired defense secretary marc esper on twitter. Thousands leave the regional capital in nagornokarabakh as fighting between azerbaijan and armenia intensifies. Terms in doha with only sports news 27 team asas champion Sergio Garcia withdrawals from this weeks tournament after testing positive for corona virus. American drug maker pfizer has released interim results show its vaccine is effective against the corona virus the news has been welcomed by scientists and World Leaders and triggered a surge on Global Markets the vaccine developed by pfizer and german start up by on tech was found to be more than 90 percent effective in preventing covert 19 among study participants no serious safety concerns were observed among the more than 43000 Party Percent across the globe a study showed just 94 confirmed cases of kevin 19 of the news has been called a great day for science and humanity and while the World Health Organization says the results are very positive its added that there is still a lot of work to be done charlie engineer reports. 1300000000. 00 doses by the end of the year thats the claim from drug makers pfizer and biotech after announcing their vaccine is more than 90 percent effective theirs is the 1st successful data from a large scale Clinical Trial and widespread vaccinations could roll out by the end of december following an application for an emergency use approval from regulators within weeks German Company biotech admit theyre still waiting on more results to further predict safety. Its true that this type of medication has no approval yet which is why we are carrying out this compatibility study with more than 40000 test persons to find out if there is any intolerance even a rare one what we can prove with this study is that the vaccine is compatible and that side effects are mild to moderate and that there are no severe side effects the news of the vaccine sent Global Stock Markets soaring scientists welcome the news of the 90 percent effectiveness much higher than been expected but also raised questions we have to know who received the vaccine in this 1st try you know and evaluate if this is some task tick results will be extended also to add the populations which are matched more than in needs for relaxing the they mean all the people people with. Who are at risk of severe infections and probably were not included in the 1st trial you as the World Health Organizations Decision Making body met in a largely Virtual Conference questions were already being raised about how any vaccine would be distributed especially to developing countries the world has come together as never before to usual these lifesaving to resign a devil or fraud abuse and im not going to be fairly as lot with. Not private communities that people are why and what reasons some people. Behind 1200000 people have now died of the virus and more than 50000000 people have reported 10000000 of them in the u. S. But the pandemic shows no signs of abating with hungry in portugal the latest countries in europe to reimpose strict measures the assembly did have one reason to celebrate the victory of joe biden means the u. S. Will be reestablishing its relationship with the w. H. O. Of the trouble began withdrawing in july the funding the u. S. Brings is key as the organization revealed although the worlds expectations of the w. H. O. Have grown dramatically the budget hasnt charlie and aljazeera who want to talk to chris smith hes a consultant virologist at Cambridge University and joins us live via skype thanks very much for being with us so these are every interim results when will we know whether the confidence has been projected by the makers is justified. Well we need more data as your report highlighted that still to come and so far we are halfway through whats called a phase 3 trial and face serious the final sort of gate keeper before something is approved or not by regulator real thorough tease now what theyve returned so far is data from having given the virus the vaccine to 40 plus 1000 people what theyre demonstrating is that in the group of people who got the placebo in other words a nonfunctional version of their vaccine there was a very high rate of infection compared to the people who got the real deal the real vaccine and that gives us confidence that it appears to be protecting that group much more than the placebo which you would expect but what it doesnt tell us for instance is a 90 percent success rate means a 10 percent failure right so we need to know who that 10 percent are who didnt respond to the vaccine because remember this virus actually has a mortality rate which is down below one percent and about 20 percent of people tend to get more severe they are well with it so if you end up with that 10 percent strongly mapping on 2 of the most Vulnerable People having this vaccine doesnt really move this much further forward on the other hand that might not be the case and so we need to know that so that this is early days its encouraging but there is a number of commentators have said a lot of work still to do and this actually is quite different from some of the other candidates explain to us how it works it into layman terms and why it might be different from a normal kind of action and that and the safety associated with it. You know this is a 1st of its kind in the past when weve made vaccines weve made them by either growing a virus or a bacterium blitzing it so you destroy it chemically having brutalized it you inject the ensuing shrapnel into the body to educate the immune system what that thing used to look like so you can make an immune response well this new vaccine actually uses the genetic code or at least part of it from the virus what theyve done is to take a short piece of the genetic message the virus uses to make part of its al to coat the socalled spike or s. Protein that it uses to engage with and invade our cells theyve wrapped that genetic code up in a layer of oil so you end up with a small oily bubble and you inject millions of these oily bubble particles into the body into a muscle and immune cells and other cells picked these are and in the same way that if i sent you a u. S. B. Stick through the post you could the envelope get the u. S. B. Stick and put it in your machine and be able to read what was on it the cells that pick up these oily bubbles can read the genetic code and they then know how to make the outer coat of the virus which they then display to the immune system which makes a corresponding immune response it makes antibodies chiefly and those antibodies are there to defend you if you encounter the corona virus for real because theyre already washing around in your blood and were you to encounter the virus for real those antibodies which are sticky molecules would glue themselves to the virus and then the cells that got infected and deactivate the virus and stop it spreading through your body now all of this is based presupposes that a that this can be rolled out quite quickly in large numbers but also that theres enough public take up what kind of levels of Public Confidence do you need in order to achieve. Success with a vaccine. Well the interesting thing here is unlike say measles where the way in which we protect the population of which everyone is vulnerable for measles is we go for a very high vaccination right we try and vaccinate 95 percent of people there. Gives her the protection or herd immunity protection to the newly born children who havent been vaccinated yet or people whove lost their immunity or cant be vaccinated but with this corona virus theres a very Discrete Group of people we know who are a very high risk theyre almost exclusively older people and people with preexisting Health Conditions that we know will mark them out as a high risk so therefore the best strategy here is to go in certainly in the initial phases of this with our limited supplies of vaccine up front and target those people who need it most because theyve actually got the most to lose theyre also more likely to be engaged with and have the greatest buy in to having the vaccine because theyve got the most to gain through having it talk to chris smith thank you very much indeed it was so good to talk to you thank you pleasure all the all this is the number of corona virus infections in the u. S. Passes 10000000 and the virus continues to spread unchecked in many states president elect joe biden has made dealing with the outbreak his 1st major priority assembling a task force of scientists and medical professionals i was there no effort to turn this page demick a room once was sworn in january 20th to get our kids back to School Safely our business is growing and our economy running for speed to get it again approved x. E. Manufactured it distributed as quickly as possible to as many americas to as Many Americans as possible free of charge will follow the science. Why cant i joins us live from wilmington delaware so might president elect biden very much focusing on how hell tackle the pandemic. Very much so and its been months in the planning hes been sitting down with Health Advisors for a long period of time now a few months ago he released a plan of action that he wanted to institute when he becomes president now that looks exceedingly likely now he use the president elect that plan will be instituted he says immediately hes sworn in on january the 20th certainly it is a wide ranging plan the basis of that is that it will have an overarching strategy what weve seen under the trumpet ministration is basically a scatter shot gun type approach leaving every state to sort out its own strategy and country in the pandemic biden wants to introduce a National Plan that will give everybody a common way in which the pandemic can be fought incidentally he warmly welcomed the potential new vaccine the news of which he was given by his Health Officials late last night but at the same time hes repeated the words of the director of the c. D. C. Saying that for the foreseeable future a mask remains a far more potent antidote to the virus then does a vaccine he had an impassioned call once again for people to wear masks saying that masks could save the lives of everybody around could save tens of thousands of lives in coming months particularly as cases spike across the United States as we move through winter and might kill the transition in the extra challenging as President Trump has not conceded yet. Indeed no and the whole process of transition obviously a very tough move but particularly because of certain stumbling blocks now one of these very importantly is a body known as the General Services administration now this is the body its a supposedly nonpartisan which actually gives the signal when the formal process of transition begins its formal task is to basically Police Buildings within washington d. C. But this is the body that will give for Example Office space to the biden. Ministration as it moves in it has to organize security clearances this huge amount of detail that has to be supplied for an Incoming Administration however the head of this body emily murphy is refusing to sign off on the transition process at this particular point now this means that nothing can formally begin and to all the General Services administration signed off on the process not to put this into a context when the bomber administration moved in post to bush the letter of administration but the letter signaling the beginning of translation was actually given at 1 oclock in the morning after the election this is a major stumbling block to the Biden Administration the Incoming Administration because unless that transition process is formally started then what they can do is incredibly limited mike hanna thank you very much. U. S. Markets have rallied following the announcement of that Major Development in pfizers Coronavirus Vaccine yes and p. 500 ended just shy of a record on monday after the close of the trading Day Industries hit hardest by the pandemic have seen the biggest gains including airlines and hotels commuters on do is in new york for us as folks im quite big moves are on the market as a result of this. There was one trader said as soon as news came out about this possible Coronavirus Vaccine he said it was a light at the end of the tunnel he said suddenly there is hope in the Financial Markets that was the word of one trader at least and we saw that on the markets all day the markets opened with that with the dow up almost 6500. 00 points or 5 percent and we pretty much sustained that throughout most of the day now in the last half hour of trading in the markets closed about 1510 minutes ago or so in the last half an hour of trading it did slide just a little bit but it still closed in the green the dow finishing a day 835. 00 points and almost 3 percent up which is still very good thats the best the dow has finished and a trading day since june 5th now the sectors that benefited the most as you can imagine are travel leisure and hospitality these are all things that saw big big gains or to be an example Carnival Cruise lines up 39 percent just on monday the Marriott Hotel chain up 14 percent United Airlines one of the Biggest Airlines in the world based in the United States up 19 percent and disney up 12 percent it just gives you an idea of how the travel industry hospitality is all seeing this potential covert back seen as a as a return to normal if you will in the near future and thats why youre seeing these the run on these stocks of these companies now there are some squat unquote stay at Home Companies that did take a hit for example companies that have done very well over the last 6 to 12 months because of the krona virus such as zoom for example they dropped 16 percent amazon 5 percent and core ox down 10 percent but the big story on wall street on monday was euphoria for lack of a better word because theres really a sense that for the short term this potential vaccine is good but also for the medium and. Long term as well but there were some traders out there that were saying listen probably wont get the vaccine readily available until early 2021 maybe even a 1st or 2nd quarter of 2021 and so some traders at the end of the day were backing off saying listen probably is not going to be a lot of unnecessary travel or what have your people returning to the office in huge numbers at least until this vaccine is readily available that still is several several months away so bottom line though is the markets reacted very positively to this news to thank you this is the news hour live from london still to come protesters and police clash on the streets of georgia claims a very intriguing in the form of soviet republic. Iraqi Security Forces hunt the gunman who opened fire on a baghdad army post. And swedish star striker is not time even a bitch shows no signs of slowing down and its really tough for the. U. S. President donald trump has sacked his defense secretary. Making the announcement on twitter as for disagreed with chums decision to send military troops to disperse black lives matter purchased in june hes being replaced by the head of the Counterterrorism Center christopher miller. Joins us live from washington d. C. I mean what do we know about. But we know that it got probably about 5 minutes notice from the chief of staff mark meadows who called them to say that the announcement was coming from the president that gives a cause of what happened to the former secretary of state Rex Tillerson when he got the same call on a foreign trip certainly we know that mark air and donald trump have not been getting on well even though donald trump described them as mark yes for essentially saying that he was always happy to please the president but the 2 went different ways particularly over the summer one on the renaming of some bases after confederate generals certainly mark esper was in favor of looking at the process of renaming some of these places but also just on the fact that donald trump had considered putting american troops on the street using the insurrection act because of some of the protests that were seeing and mark esper had said a number of events that that was not something he wanted to see so there was talk before the election that mark esper had prepared the Resignation Letter knowing that the axe was going to come particularly if donald trump got a 2nd term but no matter what the result of the election was he was expecting to go and it came on monday theres a couple of other people in the administration that donald trump has expressed concern about the head of the cia the head of the f. B. I. Both of them will probably be frantically checking twitter over the next couple of hours as well and allan in the meantime president appears to be still confident that his legal challenges will be successful. Exactly hes been preaching out in the last hour various things about some of the states that are still being disputed he said of wisconsin its looking very good needs a little time statutorily but we will. Will happen soon so what that means were not entirely sure they describe the vibe as being a