Can you request one coronavirus vaccine if you have concerns about the other? Updated Feb 18, 2021; Posted Feb 18, 2021 Jennifer Loebick, a registered nurse who works in the ICU at Fairview Hospital, receives a coronavirus vaccine at the Cleveland Clinic's main campus. (Courtesy Cleveland Clinic) Facebook Share Our readers have questions about the coronavirus vaccine, and cleveland.com is getting answers from health care experts. Q. Could I request one COVID-19 vaccine if I’m allergic to an ingredient in the other? Generally speaking, there’s little reason to make a specific request for one of the two COVID-19 vaccines that have been approved for use in the U.S., experts say. They’re very similar.