CDC Now Says Two Masks Are Better Than One The Centers for Disease Control has new virus new guidelines for us. One is making some people laugh. The other is making most smile. The first is the idea that two face masks are better than one. The CDC mask guidance relates to the addition of a mask made of cloth, worn along with a medical or surgical style mask. Lab experiments have shown that the combination results in up to 95% effectiveness in preventing the spread of the COVID-19 virus. Earlier in the week, lots of social media posts included images of people wearing a handful of masks and making fun of the idea as it began to get legs around the world.