There are 31 regional pharmacovigilance centres in France - centres régionaux de pharmacovigilance (CRPV) - which monitor and analyse all reports of unwanted medication side-effects. These can be signalled by a health professional, agreed associations, and patients - via a health ministry portal, or via a CRPV directly. The CRPV then analyses each report, and decides if the side-effect is linked to the medication, or due to an unrelated issue or cause. The data is then gathered nationally, and then added to the European database, EudraVigilance. Any serious or new reports are sent to the ANSM, which can - if deemed necessary - lead to an alert, and new precautions to take.