Culturelle expands range with Metabolism + Weight Management product Culturelle, the world’s number one-selling probiotic brand, has expanded is probiotic portfolio with its first product targeting metabolic health and weight management. The product is formulated with Lacticaseibacillus rhamnosus GG (formerly Bifidobacterium animalis subsp . lactis BPL1 (CECT 8145) strain. BPL1 is supported by a portfolio of pre-clinical and clinical evidence demonstrating its potential metabolic health and weight management benefits. Among the studies supporting the strains efficacy is a three-month randomized, parallel, double-blind, placebo-controlled trial that was published in 2019 in the International Journal of Obesity. The study, which included 126 obese adults, found that supplementation with either live or heat-killed BPL1 led to significant reductions in waist circumference (-1.75 cm in the live and -1.84 cm heat-killed groups) and the live bacterium produced statistically significant reductions in BMI versus both its baseline levels and the placebo group.