Decoding the 'chassis effect": host physiolog

<p style="text-align:justify"><strong><strong>The varied performance of genetic circuits based on host environment, termed as the &lsquo;chassis effect,&rsquo; creates uncertainty in synthetic biology applications. However, the underlying factors governing this effect are not clearly understood. Researchers from Norway and the United Kingdom have now demonstrated that genetic inverter circuit performance was directly related to physiological attributes, and not phylogenomic relatedness, in six engineered Gammaproteobacteria species. Their findings establish host physiology as a robust predictor of genetic circuit performance. </strong></strong></p>

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London , City Of , United Kingdom , Norway , South Kensington , Kensington And Chelsea , Hansc Berstein , Hansc Bernstein , Geoffs Baldwin , , Imperial College Centre For Synthetic Biology , Method Of Research , Arctic University Of Norway , Arctic Centre For Sustainable Energy , Biodesign Research , Imperial College London , Department Of Life Sciences , Professor Hans , Arctic University , Design Research , Life Sciences , College Centre , Synthetic Biology , Arctic Centre , Sustainable Energy , Host Dependent Nature , Engineered Genetic Inverter ,