that's $450 billion just from foreign profits. it does not include buy-backs. and the looming biobonanza is fuelling wall street's rally. matching the strongest first week in more than a decade. oprah winfrey this morning raising political prospects with a message for the ages last night. for young women at the golden globes. >> a new day is on the horizontal. >> and the president's tweet was like really smart. how his own words adding to critics' questions about his i fitness for office.