The book ‘Lost Connections: Uncovering the Real Causes of Depression-and the Unexpected Solutions’ narrates the personal adventure of the British-Swiss journalist, Johann Hari, who from an early age had to deal with severe depressive. What he was experiencing was not a passing sadness, his emotional despondency was persistent and severe. After 13 years of failed treatments, Hari made the decision to undertake a thorough investigation into the true origin of the depressive experience. By traveling to unexpected places and conducting more than 200 interviews with renowned doctors, psychologists, psychiatrists, and sociologists, the author uncovers some rather disturbing findings regarding the information officially shared about this disorder. For decades, the Western medical system has explained that depression is due to a chemical imbalance in the brain. The prevailing discourse mainly suggests that there is a spontaneous and significant failure in serotonin levels and, for this reason, antidepressants must be prescribed.