Does RNAi-based technology fit within EU sustainability goals? If we were farmers in Europe today, we would probably have major concerns about our future. In fact, the European Commission foresees a radical transformation of the food production system by 2030 to ensure sufficient food for the entire population produced in a sustainable and safe way for the environment and humans. The "F2F" ("Farm to Fork") strategy, in the well-known "Green Deal" policy document, should be implemented through the adoption of various practices, including the substantial decrease in the use of synthetic crop protection products and fertilizers (up to 50%) and a conversion of at least 25% of the current agricultural land to organic regime.