The world's first aerosolized inhaled adenovirus type-5 vector-based COVID-19 vaccine (Ad5-nCoV), jointed developed by CanSino Biologics (CanSinoBIO) and researchers from the Institute of Military Medicine under the Academy of Military Sciences led by Chen Wei, was proven safe in Phase-I clinical trials, the Global Times learned from CanSinoBIO on Wednesday. The trial showed that two doses of aerosol Ad5-nCoV was well tolerated, without causing any vaccine-related serious adverse events, CanSinoBIO said. The trial found that an aerosolized booster vaccination taken 28 days after the first intramuscular injection "induced strong IgG and neutralizing antibody responses," said the report of the trial, which was published on The Lancet Infectious Diseases on Monday.