How the CDC's new mask guidelines will affect Southern Colorado According to the CDC's COVID-19 Data Tracker, El Paso and Pueblo County are labeled as substantial hot spots. and last updated 2021-07-28 00:37:27-04 SOUTHERN COLORADO â The Centers for Disease Control and Prevention released new mask guidelines on Tuesday, amid concerns about the spread of the Delta variant. The CDC now recommends that people who are vaccinated against COVID-19 should still wear masks indoors and in areas with high rates of the disease. According to the CDC's COVID-19 Data Tracker, El Paso and Pueblo County are labeled as substantial hot spots.