One dose of mRNA vaccine may be sufficient for individuals previously infected with SARS-CoV-2 A recent scientific report from Israel shows how healthcare workers previously infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present with higher Immunoglobulin G (IgG) titers after receiving one dose of Pfizer–BioNTech COVID-19 vaccine in comparison to their fully vaccinated, never-infected counterparts. Conversely, the occurrence of post-vaccination infection does not increase IgG titers. The research paper is currently available on the medRxiv* preprint server. As of April 2021, Israel is the country with the highest vaccine coverage against coronavirus disease 2019 (COVID-19), and their primary approach is the use of mRNA Pfizer–BioNTech vaccine. Consequently, the impact of such herculean public health endeavor on SARS-CoV-2 transmission is now clearly visible, primarily as a substantial decrease of viral spread.