Institute for Scientific Information on Coffee: Research Provides New Insight on Functional Changes That Regular Coffee Drinking has on The Brain 1 . The findings have helped to provide a mechanistic insight into some of the effects observed in existing research on coffee; including improved motor control, increased alertness and benefits to learning and memory 1 THE HAGUE, The Netherlands, April 20, 2021published in Molecular Psychiatry and sponsored by the Institute for Scientific Information on Coffee(ISIC), provides unique insights into the functional and connectivity changes that happen within the brain of regular coffee drinkers 1. This includes findings that when at rest, regular coffee drinkers had a reduced degree of connectivity in two areas of the brain (known as the right precuneus and right insular), indicating effects such as improved motor control and alertness (helping them to be better able to react to a stimulus), in comparison to non-coffee drinkers